Link AVC - Application View Controller

AVC is a multiplatform, fully automatic, live connection among graphical interface widgets and application variables for the python language. AVC supports in a uniform way the most popular widget toolkits: GTK, Qt3, Qt4, Tk, wxWidgets. AVC is a python module that can be imported by any python application.

see also
pigg Python Interface Generator for Gtk (pigg) provides a pygtk implementation of the MVC pattern.